Photo-induced thiol–ene reactions for late-stage functionalization of unsaturated polyether macrocycles: regio and diastereoselective access to macrocyclic dithiol derivatives
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چکیده
منابع مشابه
Diversity-oriented synthesis of analogues of the novel macrocyclic peptide FR-225497 through late stage functionalization
A concise synthetic approach to a class of biologically interesting cyclic tetrapeptides is reported which involves a late-stage functionalization of a macrocyclic scaffold through cross metathesis in an attempt to create diversity. The utility of this protocol is demonstrated through the preparation of three structural analogues of the important naturally occurring histone deacetylase inhibito...
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ژورنال
عنوان ژورنال: Organic & Biomolecular Chemistry
سال: 2020
ISSN: 1477-0520,1477-0539
DOI: 10.1039/c9ob02375e